What is the starting dose for metoclopramide?

Metoclopramide is an antiemetic commonly used for the treatment of nausea and vomiting, as well as for gastric motility disorders. The typical starting dose for this medication, particularly for adults, is 10 mg given up to three times daily, which aligns with the choice indicating 10 mg every 8 hours.

This dosing approach is designed to ensure effective therapeutic levels while minimizing the risk of side effects, which may include sedation, fatigue, or extrapyramidal symptoms. Starting at 10 mg allows health care providers to assess the patient’s response and tolerance before making any necessary adjustments to the dosage.

Other dosing options, such as 5 mg every 6 hours, 15 mg every 12 hours, or 20 mg every 24 hours, do not reflect the standard initial dosing regimen for metoclopramide. Lower doses may not adequately control symptoms, while higher doses could increase the risk of adverse effects without providing additional therapeutic benefit. Thus, starting with 10 mg every 8 hours offers a balanced approach to treatment.