What is a common symptom of DIC affecting urinary output?

In disseminated intravascular coagulation (DIC), one of the physiological changes that occurs is a disruption in the normal clotting process, which can lead to widespread microvascular clotting and ultimately result in organ dysfunction. The kidneys are particularly affected due to their sensitivity to changes in blood flow and perfusion.

When DIC occurs, the formation of microclots can impede blood flow to the kidneys, causing renal ischemia and decreasing their ability to filter blood effectively. This reduced perfusion can manifest as a decrease in urinary output, known as oliguria. In severe cases, urinary output may cease altogether, leading to anuria. Thus, decreased urine output is a common symptom in patients experiencing DIC, reflecting the compromise in kidney function due to inadequate blood supply. This symptom serves as a crucial clinical indicator of the severity of the condition and the impact it has on organ systems, including the kidneys.